Publications

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Filanesib / Multiple Myeloma

07/19/2016

PubMed.gov

A phase 1 dose-escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma.

Chari A., et al.

Encorafenib / Cancer

07/01/2016

ESMO World Congress of Gastrointestinal Cancer

Combination of Encorafenib and Cetuximab With or Without Alpelisib in Patients With Advanced BRAF-Mutant (BRAFm) Colorectal Cancer: Phase 2 Results

J. Tabernero, et al.

Binimetinib / Cancer

06/06/2016

American Society of Clinical Oncology Meeting

Results of NEMO: A phase III trial of binimetinib (BINI) vs dacarbazine (DTIC) in NRAS-mutant cutaneous melanoma

R. Dummer, et al.

Encorafenib / Cancer

06/01/2016

American Society of Clinical Oncology Meeting

Phase 2 results: encorafenib (ENCO) and cetuximab (CETUX) with or without alpelisib (ALP) in patients with advanced BRAF-mutant colorectal cancer (BRAFm CRC)

J. Tabernero, et al.

Binimetinib / Cancer

01/21/2016

American Society of Clinical Oncology GI 2016

A Phase I Study of MEK162 and FOLFOX in chemotherapy-resistant metastatic colorectal cancer

M. Cho, et al.

Filanesib / Multiple Myeloma

12/07/2015

American Society of Hematology Annual Meeting 2015

Phase 2 Study of Carfilzomib With or Without Filanesib in Patients With Advanced Multiple Myeloma (MM)

J. Zonder, et al.

Filanesib / Multiple Myeloma

12/06/2015

American Society of Hematology Annual Meeting 2015

Phase 1 Study of the Novel Kinesin Spindle Protein Inhibitor Filanesib + Carfilzomib in Patients with Relapsed and /or Refractory Multiple Myeloma (RRMM)

J. Shah, et al.

Filanesib / Multiple Myeloma

12/05/2015

American Society of Hematology Annual Meeting 2015

Mechanisms Underlying the Synergistic Interaction of Filanesib with Pomalidomide and Dexamethasone (FPD) in Multiple Myeloma

S. Hernandez-Garcia, et al.

Binimetinib / Cancer

09/28/2015

European Cancer Congress

A Phase 1b/2 Study of Ribociclib (LEE011; CDK4/6 inhibitor) in Combination With Binimetinib (MEK162; MEK inhibitor) in Patients With NRAS‐Mutant Melanoma

C. van Herpen, M.D., Ph.D, et al.

Binimetinib / Cancer

09/27/2015

European Cancer Congress

LOGIC2: Phase 2, Multi-center, Open-label Study of Sequential Encorafenib/Binimetinib Combination Followed by a Rational Combination with Targeted Agents After Progression, to Overcome Resistance in Adult Patients with Locally Advanced or Metastatic BRAF V600 Melanoma

R. Dummer, M.D., et al.